biostatistics

Quantification of Variation in Reading Immunohistochemical Assays

Semiquantitative immunohistochemical assays have been used with increasing frequency. This study was designed to investigate the reproducibility of such measurements by observing how the measured level varied du.e to (a) the choice of tissue sample …

Ras Oncogene Protein Product in Ulcerative Colitis

Increased expression of cellular oncogenes has been linked to malignant-transformation. To investigate the role of oncogenes in the malignant transformation of colonic epithelium in ulcerative colitis, we compared the levels of ras oncogene protein …

Relationship between Ras Oncogene Expression and Clinical and Pathological Features of Colonic Carcinoma

In order to investigate the value of ras oncogene expression as a prognostic indicator in colonic adenocarcinoma, we evaluated the level of ras gene protein product (p21) in the available material of 109 surgical specimens resected at our institution …

Experience with 647 consecutive tumors of the duodenum, ampulla, head of the pancreas and distal common bile duct

Between 1946 and 1987, 647 patients with periampullary tumors were diagnosed at the University of Chicago Medical Center. These included 549 tumors located in the head of the pancreas, 40 in the distal common bile duct, 29 in the duodenum, and 29 at …

Ras oncogene protein p21 levels parallel malignant potential of different human colonic benign conditions

Ras oncogenes are a specific family of genes believed to play a role in malignant transformation and tumor growth in humans. To gain a better understanding of the role these oncogenes may play in malignant transformation, we evaluated the levels of a …